Bioidentical Hormone Replacement Therapy for Men (BHRT)
Better hormones. Better energy. Better you.
Low energy, declining strength, stubborn weight, brain fog, poor sleep, and changes in libido can all be signs that your hormones are out of balance. Nava uses advanced testing and physician-led care to identify what’s happening and build a treatment plan around your body.
What Is Bioidentical Hormone Replacement Therapy?
BHRT uses hormones that are chemically identical in molecular structure to those the human body produces naturally. They are typically derived from plant sources such as yams and soy, then compounded or manufactured to match the exact structure of endogenous hormones like testosterone, estrogen, and progesterone.
The distinction from synthetic hormone formulations is structural. Bioidentical hormones are designed to bind to the body’s hormone receptors in the same way as the hormones your body makes. This structural match is the basis for individualized dosing: because the formulation mirrors the body’s own chemistry, clinicians can titrate doses to achieve target physiological levels rather than applying a one-size-fits-all protocol.
Who May Be a Candidate for Male BHRT?
BHRT is not appropriate for every man experiencing fatigue or low libido. Candidacy is determined through clinical evaluation, not symptoms alone. A man may be considered for BHRT when:
- Lab testing confirms hormone levels that are clinically deficient or outside optimal ranges
- Symptoms are consistent with the identified deficiency and not better explained by another condition
- A full health history review finds no contraindications
- The patient and clinician agree that the expected benefits justify the treatment and its monitoring requirements
How it works
The Nava BHRT Process: From Evaluation to Treatment
Nava’s approach to male hormone therapy follows a structured clinical pathway. There are no shortcuts in the sequence: treatment does not begin until evaluation is complete and clinically justified.
Comprehensive Diagnostic Evaluation
We analyze 70+ biomarkers through our national lab partner network to pinpoint exactly what’s driving your symptoms.
Clinical Consultation and Treatment Planning
A medical provider and functional nutritionist review your results together and build a clear picture of your hormonal health.
Get your personalized protocol
Your provider reviews your results and builds a care plan tailored to your body, symptoms, and goals.
Benefits of BHRT
Potential Benefits of BHRT for Men
When BHRT is clinically indicated and properly monitored, research suggests it may support improvements across several areas of health and function. It is important to understand that individual results vary, and outcomes depend on the specific deficiency being treated, the delivery method, dosing accuracy, and adherence to monitoring protocols. Benefits that have been studied in men with confirmed hormone deficiencies include:
Energy and vitality
Restoring testosterone to physiological levels is associated with reduced fatigue and improved physical capacity in men with documented deficiency
Body composition
Testosterone plays a direct role in lean muscle maintenance and fat metabolism; treatment may support improvements in muscle mass and body fat distribution when combined with appropriate nutrition and exercise
Libido and sexual function
Testosterone is a primary driver of male sexual desire; restoration to optimal levels may improve libido and, in some cases, contribute to better erectile function
Mood and cognitive clarity
Hormone optimization has been associated with improvements in mood stability, motivation, and cognitive performance in men with deficiency
Bone density
Adequate testosterone and estrogen levels are important for maintaining bone mineral density, particularly as men age
Metabolic markers
Balanced hormones may support insulin sensitivity and healthy body weight, though these effects are influenced by lifestyle factors as well
Clinical note: The evidence base for BHRT in men is strongest for testosterone replacement in men with confirmed hypogonadism. Benefits for other hormones and in men without confirmed deficiency are less well-established. Nava’s clinicians will discuss the evidence relevant to your specific situation during your consultation.
Getting started
Your path to better energy, strength, and performance.
Low energy, stubborn weight, brain fog, low libido, poor sleep, or changes in performance can all be signs that something is off. Nava starts with advanced labs to uncover what may be driving your symptoms and builds a personalized plan to help you feel stronger, sharper, and more like yourself again.
Nava advanced diagnostic labs and care plan
Start with advanced diagnostic labs and get a personalized plan for energy, hormones, weight, sexual health, performance, and long-term vitality.
and personalized treatment plan
Advanced biomarker testing
Comprehensive 70+ biomarker testing helps uncover what may be driving symptoms.
Meet with medical experts
Review your results with a medical provider and functional nutritionist to build a personalized plan.
Treatments tailored to you
Get personalized treatment recommendations based on your labs and goals, available directly through Nava.
Personalized plan and tracking
Your data guides a doctor-led plan including your BioAge score, and health dashboard access.
Complete Care
Your health is personal, and so is our approach.
We design care around you.
Most longevity companies hand you data. We hand you specialists who know what to do with it. At-home tests and AI apps can tell you something’s off. Nava tells you why, what it means for your life, and exactly how to fix it, with board-certified physicians who have done this for 65,000 clients over 12 years.
70+ biomarker lab monitoring
A standard physical looks at fewer than 20 markers, enough to catch disease but not enough to explain why you feel the way you do. Nava runs a full panel across hormones, thyroid, metabolism, inflammation, and cardiovascular health, then retests as your plan progresses so you can see what’s actually changing. Your results live in one place, tracked over time, not scattered across portals from three different offices.
Nutrition & health guidance
Most lab results end with a recommendation to eat better. Yours ends with a registered dietitian who has read your panel and builds nutrition, supplementation, and lifestyle guidance around what your specific markers show. It’s a full hour, and it adjusts as your labs move.
Consistent clinical oversight
You work with the same board-certified physician, not whoever is available that week. They know your history, what you’ve already tried, and how your body responded to the last change, which is what makes the next decision a better one. Every result is interpreted by a clinician, never an algorithm.
Dose refinement & optimization
Any doctor can write you a prescription. Finding the dose that actually works for your body takes follow-up labs, honest conversation about how you feel, and a provider willing to adjust rather than leave you on a starting dose indefinitely. If your plan includes treatment, that refinement process is built in.
Ongoing access to your care team
Questions don’t wait for your next appointment. Message your care team through the Nava app when something changes, a side effect shows up, or you need to make sense of a result. You’ll get a response from someone who already knows your case.
Why Medically Supervised BHRT Matters
The availability of testosterone and hormone products through online clinics and direct-to-consumer platforms has grown substantially. For some men, this accessibility is appealing. The clinical reality is more nuanced.
Hormone therapy that is initiated without comprehensive baseline testing, delivered without individualized dosing, or maintained without regular monitoring is not the same treatment.
Nava’s model is built around this standard. Since 2014, Nava’s clinical team has provided hormone optimization as part of a broader functional medicine approach, not as a standalone prescription service. The distinction matters for patient safety and for treatment outcomes.
What if your medical team actually helped you live a longer, healthier life?
Lives Improved
Client Satisfaction
Biomarkers Tested
Members Improved Biomarkers in 3 Months
Benefits of BHRT
Hormones Commonly Addressed in Male BHRT
While testosterone is the primary focus of male hormone therapy, Nava’s clinicians evaluate the full hormonal picture before recommending any treatment protocol.
Testosterone
Drives muscle mass, libido, energy, mood, and cognition. The primary target in andropause and low-T treatment, and the hormone most commonly deficient in men seeking evaluation.
Estradiol (E2)
Supports bone density, cardiovascular function, and libido. When estrogen is elevated relative to testosterone, it can affect body composition, mood, and sexual function.
Progesterone
Testosterone is a primary driver of male sexual desire; restoration to optimal levels may improve libido and, in some cases, contribute to better erectile function
Mood and cognitive clarity
Hormone optimization has been associated with improvements in mood stability, motivation, and cognitive performance in men with deficiency
Bone density
Adequate testosterone and estrogen levels are important for maintaining bone mineral density, particularly as men age
Metabolic markers
Balanced hormones may support insulin sensitivity and healthy body weight, though these effects are influenced by lifestyle factors as well
Clinical note: The evidence base for BHRT in men is strongest for testosterone replacement in men with confirmed hypogonadism. Benefits for other hormones and in men without confirmed deficiency are less well-established. Nava’s clinicians will discuss the evidence relevant to your specific situation during your consultation.
How BHRT is Administered
Treatment Delivery of BHRT
BHRT can be administered through several delivery methods. The right choice depends on the hormones being addressed, your absorption profile, lifestyle preferences, and clinical guidance. Each method has a distinct absorption and release profile. Your Nava clinician will recommend the most appropriate option based on your individual clinical picture, not convenience alone.
Injections
Administered intramuscularly or subcutaneously, typically on a weekly or bi-weekly schedule. Injections offer precise dosing control and are among the most common delivery methods for testosterone replacement.
Pellets
Small pellets inserted subcutaneously, usually in the hip or buttock, that release hormones steadily over 3 to 6 months. A good option for men who prefer not to manage daily or weekly administration.
Topical creams and gels
Applied to the skin daily and absorbed transdermally. Offer flexible dosing adjustments and are commonly used for testosterone and DHEA.
Patches
Worn directly on the skin and changed every one to two days. Provide a consistent, steady-state hormone delivery without injections or daily application routines.
Oral and sublingual
Taken by mouth or dissolved under the tongue. Used for select hormones where oral absorption is clinically appropriate; chosen primarily for convenience.
Metabolic markers
Balanced hormones may support insulin sensitivity and healthy body weight, though these effects are influenced by lifestyle factors as well
Clinical note: The evidence base for BHRT in men is strongest for testosterone replacement in men with confirmed hypogonadism. Benefits for other hormones and in men without confirmed deficiency are less well-established. Nava’s clinicians will discuss the evidence relevant to your specific situation during your consultation.
What Our Clients Say
“Becoming a member of Nava Health & Vitality has been the best thing I’ve ever done. Every time I arrive I’m greeted by friendly people who are knowledgeable and professional.”
“I was always looking for a healthier life style and stay away from modern medicines with all there side affects. These years have been a great experience. I highly recommend this for everyone who wants better health.”
“The attention to my health needs has been a wonderful change from my PCP. I always look forward to meeting with my nutritionist, Ryan. Samantha has helped me reach some goals I thought I could not.”
“Since I made the decision to take my health into my own hands, I am feeling so much better. I went to Nava with no energy, brain fog, stomach issues and aches and pains. My regular doctors found nothing and haven’t addressed anything. I had complete blood work here and discovered hormone imbalances and other issues that are all being addressed. ”
Have questions about hormone imbalance in men?
When Should Men Seek a Clinical Evaluation for Hormone Imbalance?
Not every symptom requires immediate investigation, but certain patterns warrant a clinical conversation sooner rather than later. The Endocrine Society recommends evaluation for men with low libido, erectile dysfunction, infertility, unexplained fatigue, mood changes, or reduced muscle mass, particularly when symptoms are persistent and not explained by another known condition.
Consider scheduling a hormone evaluation if you are experiencing:
- Fatigue or low energy that has persisted for several months and does not improve with rest
- A noticeable decline in libido or sexual function
- Difficulty maintaining muscle mass or unexplained increases in body fat
- Mood changes, including persistent low mood, irritability, or reduced motivation
- Cognitive changes such as brain fog, poor concentration, or memory lapses
- Sleep disruption, particularly when combined with other symptoms on this list
- Fertility concerns
Symptoms that began after starting a new medication, particularly opioids or corticosteroids
Seek prompt medical attention if you experience sudden, severe changes in sexual function, significant mood changes, or symptoms that may indicate a pituitary or testicular condition, such as visual changes, severe headaches, or testicular pain.
The right time to seek evaluation is when symptoms are affecting your quality of life, regardless of age. Waiting to see whether things improve on their own is a reasonable approach for mild, short-lived symptoms. For persistent or worsening changes, a clinical evaluation is the appropriate next step.
What Happens If Testing Identifies a Hormone Imbalance?
A confirmed hormone imbalance does not automatically mean hormone therapy is the right next step. The appropriate response depends on which hormones are out of range, the likely cause, the severity of symptoms, your overall health, and your personal goals.
For some men, addressing lifestyle factors, treating an underlying condition such as thyroid dysfunction or sleep apnea, or correcting nutritional deficiencies may be sufficient to restore hormonal balance. For others, where testing and a thorough clinical evaluation identify a clinically appropriate hormone deficiency, a Nava provider may discuss medically supervised hormone therapy as part of a broader care plan.
If you and your provider determine that hormone therapy may be appropriate, the next step is a detailed conversation about options, candidacy, risks, expected outcomes, and the monitoring required to ensure safe, effective care.
Can men have hormone imbalances?
Yes. Hormone imbalances affect men at every age, though they become more common with age. Testosterone deficiency is the most frequently diagnosed, but imbalances in thyroid hormones, cortisol, estrogen, and other markers are also clinically significant in men. Symptoms are often attributed to stress or aging before a hormonal cause is considered.
What are the most common symptoms of hormone imbalance in men?
The most commonly reported symptoms include persistent fatigue, reduced libido, erectile dysfunction, loss of muscle mass, weight gain, poor sleep, mood changes, and difficulty concentrating. These symptoms overlap with many other conditions, which is why lab testing is essential for an accurate diagnosis.
Can low testosterone cause fatigue, weight gain, and erectile dysfunction?
Low testosterone is associated with all three. However, the Endocrine Society’s guidelines are clear that these symptoms are not specific to testosterone deficiency alone. Thyroid dysfunction, cortisol imbalance, metabolic issues, and other factors can produce identical symptoms. A comprehensive evaluation is needed to identify the actual cause.
How is hormone imbalance diagnosed in men?
Diagnosis requires both consistent symptoms and laboratory confirmation of abnormal hormone levels. Per NIH clinical guidance, testosterone should be measured on at least two separate occasions using fasting morning blood samples. A full evaluation also includes assessment of related hormones and markers to identify contributing factors.
Can you prescribe Testosterone via telehealth?
Yes. In the states where we are licensed, our providers can prescribe testosterone (TRT) and other hormone therapies if your lab results and medical history indicate a clinical deficiency. We strictly adhere to all federal and state regulations regarding controlled substances to ensure your treatment is both legal and safe.
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